Genialis Expands Portfolio of Multi-Omics Data Analysis Workflows to Extend Applications for Drug Discovery

Genialis’ single-click visual analytics solution complements
single-day RNA-seq library preparation

which provides AI-driven, platform-enabled data integration solutions to
help accelerate drug discovery, today announced a partnership with Roche
to provide researchers with a complete, streamlined next-generation
sequencing (NGS) workflow for gene expression profiling. By using
Genialis, Roche KAPA RNA HyperPrep Kit* customers now have end-to-end
support from sample through analysis. Genialis and Roche are debuting
the integrated solution at the 68th Annual Meeting of the American
Society of Human Genetics (ASHG 2018), which takes place October 16-20
in San Diego, CA.

Biological tissue samples like cancer stem cells, blood plasma, and
serum are valuable sources of material for translational oncology
research; the complexity of generating and analyzing NGS-based
expression data from these samples, however, remains one of the most
restrictive bottlenecks to elucidating the molecular mechanisms of
disease progression, drug activity, and therapeutic response.

To address these challenges, the new RNA-seq analysis workflow combines
Roche’s KAPA RNA HyperPrep Kits— a robust, single-day RNA-seq library
preparation that increases the efficiency and sensitivity of sequencing
low-input samples— with the Genialis software platform. Genialis, which
provides an automated, “single-click” data processing pipeline and
guided interpretation workflows for gene expression analyses, supports
the entire family of KAPA RNA HyperPrep Kits.

“The insights researchers can derive from high-throughput RNA sequencing
data are critical to furthering the advancement of drug discovery and
precision medicine,” said Rafael Rosengarten, co-founder and Chief
Executive Officer of Genialis. “That said, knowing how to make sense of
those data can be overwhelming, especially for scientists without
computational backgrounds. Through this partnership, researchers will
have much more control over their data, and be able to quickly generate
and disseminate actionable information to push their research forward.”

Genialis will showcase the data analysis workflow at ASHG 2018 in the
San Diego Convention Center exhibit hall, booth #741. Information on
Roche Sample Prep Solutions for RNA-Seq, and joint software
demonstrations with Genialis will be available at the Roche Sequencing &
Life Science exhibit, booth #715.

In addition, Genialis and Roche will co-sponsor a webinar entitled
“Defining a Multi-Omics Target Discovery Framework for High-Risk
Cancers,” on November 27th. In this presentation, Stephen C. Mack,
Assistant Professor at Baylor College of Medicine, will illustrate how
his innovative approach to integrating RNA-seq and ChIP-seq data enabled
the discovery of novel drug targets in chemotherapy-resistant cancer
models. To register for the webinar, visit genial.is/RocheWebinar.

To learn more about the integrated Genialis + KAPA RNA-Seq data analysis
workflow, please visit genial.is/RocheWorkflow.

* For Research Use Only. Not for use in diagnostic procedures.


Genialis helps translational and biopharma research teams accelerate the
discovery of targeted therapeutics. Our cloud-based platform simplifies
the analysis, integration, and management of multi-omics data,
empowering researchers who lack specialized bioinformatics knowledge go
from sequence to insights in minutes. For more information about
Genialis, please visit us at www.genialis.com
and connect with us on LinkedIn.


Vuturo Group for Genialis:
Vuturo, 415-689-8414
M. Feaster
Director of Commercial Strategy


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